Roxithromycin EP Impurity D CAS 134931-00-3
| CAS No. | 134931-00-3 |
| Molecular Formula | C41H76N2O15 |
| Molecular Weight | 837.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Roxithromycin EP Impurity D (CAS 134931-00-3), a pharmacopoeial impurity reference standard (molecular formula C41H76N2O15, MW 837.05 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C41H76N2O15, Roxithromycin EP Impurity D contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 837.05 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Roxithromycin EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C41H76N2O15 |
| Molecular Weight | 837.05 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Related Roxithromycin Standards
- Roxithromycin (CAS 80214-83-1)
- Roxithromycin EP Impurity J (CAS 134834-12-1)
- Roxithromycin Impurity 24 (CAS CATO-C4X-130324)
- Roxithromycin-d7 (CAS CATO-C4X-130322)
- Roxithromycin-d7 (CAS CATO-CCAD300664)
- Roxithromycin impurity 28 (CAS CATO-C4X-130328)
- Roxithromycin Impurity 25 (CAS 1094780-37-6)
- Roxithromycin impurity 30 (CAS CATO-C4X-130330)
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Why CATO?
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