n-(4-Chloro-2-fluorobenzyl)piperidin-4-amine dihydrochloride CAS 1349708-93-5
| CAS No. | 1349708-93-5 |
| Molecular Formula | C12H16ClFN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
n-(4-Chloro-2-fluorobenzyl)piperidin-4-amine dihydrochloride (CAS 1349708-93-5), molecular formula C12H16ClFN2HCl and molecular weight 279.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of n-(4-Chloro-2-fluorobenzyl)piperidin-4-amine dihydrochloride (C12H16ClFN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), n-(4-Chloro-2-fluorobenzyl)piperidin-4-amine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16ClFN2 2*HCl |
| Molecular Weight | 279.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related n Standards
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Recommended Standards
- 1-Methylindoline-4-carbonitrile hydrochloride (CAS 1956382-90-3)
- 4-Allyl-5-((4-chloro-2-methylphenoxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 21358-24-7)
- 2-Chloro-N,4-dimethylnicotinamide (CAS 1706461-82-6)
- 3-Chloro-1-(tetrahydrofuran-2-yl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 1707369-96-7)
- 2-Chloro-4-(phenylamino)quinoline-3-carbonitrile (CAS 246546-76-9)
- 4-(4-Bromobutyl)-1-methyl-1h-pyrazole (CAS 1343174-56-0)
- Statine (CAS 49642-07-1)
- n-(4-Methoxybenzyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 65875-42-5)
- 2-Amino-3-(chloromethyl)-6-(difluoromethyl)isonicotinic acid (CAS 1806022-15-0)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
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