2-Chloro-4-(phenylamino)quinoline-3-carbonitrile CAS 246546-76-9
| CAS No. | 246546-76-9 |
| Molecular Formula | C16H10ClN3 |
| Molecular Weight | 279.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-4-(phenylamino)quinoline-3-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-4-(phenylamino)quinoline-3-carbonitrile (CAS 246546-76-9) is a high-purity analytical reference standard with the molecular formula C16H10ClN3 and a molecular weight of 279.72 g/mol.
Structurally, 2-Chloro-4-(phenylamino)quinoline-3-carbonitrile (C16H10ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 279.72 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10ClN3 |
| Molecular Weight | 279.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-2-(3-methoxypropyl)-1-oxo-isoquinoline-4-carbaldehyde (CAS 1018250-82-2)
- 2-Chloro-3-(1H-indol-3-yl)-quinoxaline (CAS 1146080-41-2)
- 6-Chloro-N-(3,4-dimethoxybenzyl)pyridazin-3-amine (CAS 1155466-26-4)
- Ethyl 2-(6-chloro-2-methyl-4-oxoquinolin-1(4H)-yl)acetate (CAS 1171940-80-9)
- Ethyl 2-(6-chloro-8-methyl-4-oxoquinolin-1(4H)-yl)acetate (CAS 1172066-32-8)
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Recommended Standards
- 2-(5-Chloro-2-hydroxyphenyl)hexahydro-1h-isoindole-1,3(2h)-dione (CAS 314030-19-8)
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- 2-(4-Chlorophenyl)-5-morpholino-2,4-dihydro-3H-pyrazol-3-one (CAS 92026-67-0)
- 2-Chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide (CAS 3608-86-4)
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- 4-Amino-N-(3-((5-chloro-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CAS 1604811-59-7)
- 6-Bromo-3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1393330-64-7)
- N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-nitro(methylsulfanyl)methanimidamide (CAS 1823194-68-8)
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- (2S)-2-(tert-butoxycarbonylamino)-3-cyclobutyl-propanoic acid (CAS 478183-60-7)
- 3-[((S)-2-Amino-propionyl)-ethyl-amino]-piperidine-1-carboxylic acid tert-butyl ester (CAS 1354026-69-9)
- (R)-N-METHYLAZEPAN-3-AMINE (CAS 197086-46-7)
- Angiotensin II Antipeptide (CAS 121379-63-3)
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