2-(2,4-Difluorobenzoyl)benzoic acid CAS 135030-72-7
| CAS No. | 135030-72-7 |
| Molecular Formula | C14H8F2O3 |
| Molecular Weight | 262.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2,4-Difluorobenzoyl)benzoic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(2,4-Difluorobenzoyl)benzoic acid (CAS 135030-72-7) is a high-purity analytical reference standard with the molecular formula C14H8F2O3 and a molecular weight of 262.21 g/mol.
The molecular framework of 2-(2,4-Difluorobenzoyl)benzoic acid (C14H8F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2,4-Difluorobenzoyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F2O3 |
| Molecular Weight | 262.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Difluorobenzoyl Standards
- 2-(3,5-Difluorobenzoyl)benzoic acid (CAS 1276024-26-0)
- 2-(3,4-Difluorobenzoyl)benzoic acid (CAS 376618-23-4)
- 4-(2,4-Difluorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide (CAS 692287-83-5)
- 2-(2,5-Difluorobenzoyl)-3-methylpyridine (CAS 1187165-68-9)
- (2,6-Difluorobenzoyl)-l-valine (CAS 956684-24-5)
- cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid (CAS 289911-76-8)
- cis-2-(3,5-Difluorobenzoyl)cyclohexanecarboxylic acid (CAS 844856-71-9)
- 1-(2,4-Difluorobenzoyl)piperidine-4-carboxylic acid (CAS 700815-59-4)
Recommended Standards
- 2,3-Dimethyl (2R,3R)-rel-1,2,3,4-Butanetetracarboxylate (CAS 138405-05-7)
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- Methyl 5-(trifluoromethyl)thiazolo[5,4-b]pyridine-2-carboxylate (CAS 1440427-85-9)
- n-((3-Bromothiophen-2-yl)methyl)pentan-1-amine (CAS 1248722-52-2)
- 2-Iodo-5-methoxy-1,3-dimethylbenzene (CAS 90609-47-5)
- 5-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190316-01-8)
- 6-Bromo-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydronaphthalene-1-carbonitrile (CAS 1620317-78-3)
- (3-Cyclopropoxy-5-(methylthio)phenyl)methanamine (CAS 1243444-03-2)
- 2,6-Dibromo-3-fluoroanisole (CAS 1803783-87-0)
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- Echinocandin B (CAS 54651-05-7)
- 7-(1-Aminocyclopropyl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 123160-52-1)
- 4-CHLORO-5-METHYLBENZENE-1,3-DIOL (CAS 3446-05-7)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
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