Posaconazole Impurity 280 CAS 1350560-52-9

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.1350560-52-9
Molecular FormulaC17H22F2O3
Molecular Weight312.35 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Posaconazole Impurity 280 CAS 1350560-52-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 312.35 g/mol gives Posaconazole Impurity 280 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Posaconazole Impurity 280 (CAS 1350560-52-9) is a certified pharmaceutical impurity reference standard with the molecular formula C17H22F2O3 and a molecular weight of 312.35 g/mol.

Based on its molecular formula C17H22F2O3, Posaconazole Impurity 280 contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 312.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Posaconazole Impurity 280 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H22F2O3
Molecular Weight312.35 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing

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