Posaconazole Impurity 110 CAS 74852-61-2
| CAS No. | 74852-61-2 |
| Molecular Formula | C17H19N3O3 |
| Molecular Weight | 313.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Posaconazole Impurity 110 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Posaconazole Impurity 110 (CAS 74852-61-2, C17H19N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C17H19N3O3, Posaconazole Impurity 110 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 313.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O3 |
| Molecular Weight | 313.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 3 |
Related Posaconazole Standards
- Posaconazole Impurity 166 (CAS 1631169-28-2)
- Posaconazole Impurity 280 (CAS 1350560-52-9)
- Posaconazole impurity 236 (CAS CATO-C4X-1208236)
- Posaconazole impurity 237 (CAS CATO-C4X-1208237)
- Posaconazole impurity 238 (CAS CATO-C4X-1208238)
- Posaconazole impurity 239 (CAS CATO-C4X-1208239)
- Posaconazole impurity 240 (CAS CATO-C4X-1208240)
- Posaconazole impurity 241 (CAS CATO-C4X-1208241)
Recommended Standards
- Palbociclib Impurity 156 (CAS CATO-C4X-1125156)
- Esomeprazole impurity 27 (CAS CATO-C4X-125527)
- Erlotinib Impurity 80 (CAS 2518426-66-7)
- Omeprazole Impurity 46 (CAS CATO-C4X-125546)
- Bromfenac Impurity 72 (CAS 61941-63-7)
- Bromfenac Impurity 62 (CAS CATO-C4X-200262)
- Ziprasidone Impurity 21 (CAS 118306-76-6)
- 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 61776-82-7)
- Ethyl 2-(benzyloxy)-4-(trifluoromethyl)benzoate (CAS 1823511-40-5)
- N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-3-methylbutanamide (CAS 477885-86-2)
- 2-Fluoro-5-isopropoxyaniline (CAS 99717-08-5)
- 5-Methyl-2-(m-tolyl)isoxazol-3(2H)-one (CAS 61563-92-6)
- N-(1-Acetyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)acetamide (CAS 90237-93-7)
- Nonapeptide-1 (CAS 158563-45-2)
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