1-(2-Cyclohexyl-2-hydroxyethyl)-3-(thiophen-2-yl)urea CAS 1351608-96-2

Description

The occurrence of 1-(2-Cyclohexyl-2-hydroxyethyl)-3-(thiophen-2-yl)urea is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(2-Cyclohexyl-2-hydroxyethyl)-3-(thiophen-2-yl)urea (CAS 1351608-96-2) is a high-purity analytical reference standard with the molecular formula C13H20N2O2S and a molecular weight of 268.38 g/mol.

The molecular framework of 1-(2-Cyclohexyl-2-hydroxyethyl)-3-(thiophen-2-yl)urea (C13H20N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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