Lamotrigine impurity 20 CAS 136565-76-9
| CAS No. | 136565-76-9 |
| Molecular Formula | C9H7Cl2N5O |
| Molecular Weight | 272.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lamotrigine impurity 20 (CAS 136565-76-9), a pharmacopoeial impurity reference standard (molecular formula C9H7Cl2N5O, MW 272.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lamotrigine impurity 20 (C9H7Cl2N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 272.09 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2N5O |
| Molecular Weight | 272.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lamotrigine Standards
- Lamotrigine Impurity 11 (CAS CATO-C4X-167211)
- Lamotrigine Impurity 13 (CAS CATO-C4X-167213)
- Lamotrigine Impurity 14 (CAS CATO-C4X-167214)
- Lamotrigine impurity 21 (CAS CATO-C4X-167221)
- Lamotrigine-13C3,d3, Major (CAS 1246815-13-3)
- Lamotrigine-d3 (CAS 1132746-94-1)
- Lamotrigine-13C3 (CAS 1188265-38-4)
- Lamotrigine EP Impurity D (CAS 661463-79-2)
Recommended Standards
- zoledronic acid (CAS 118072-93-8)
- Zoledronic Acid Impurity 10 (CAS CATO-C4X-201510)
- methyl 2-(2-bromo-3-pyridyl)-2,2-difluoro-acetate (CAS 2761389-76-6)
- 3-Hydroxy Anagrelide (CAS 733043-41-9)
- Zopiclone Impurity 8 (Mixture of Diastereomers) (CAS CATO-C4X-12388)
- Difluprednate Impurity N1 (CAS 23640-96-2)
- Triptorelin Impurity (Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) (CAS CATO-C4X-186211)
- 3,5-Dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyrazine (CAS 151075-74-0)
- (4S,4'S)-4,4'-Di(S)-sec-butyl-1,1'-di-p-tolyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole (CAS 2374958-77-5)
- 3-tert-Butylmorpholine (CAS 1260664-66-1)
- 3-[3-(2-methoxyethoxy)phenyl]prop-2-yn-1-ol (CAS 1178764-00-5)
- 4-Ethyl-3-(2-iodophenyl)-1h-pyrazol-5-amine (CAS 1187561-46-1)
- 4-(2-Amino-4-thiazolyl)phenol (CAS 57634-55-6)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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