| CAS No. | 1352209-43-8 |
| Molecular Formula | C8H3Cl2F3O |
| Molecular Weight | 243.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-(4-chloro-3-fluorophenyl)-2,2-difluoroethan-1-one.
2-Chloro-1-(4-chloro-3-fluorophenyl)-2,2-difluoroethan-1-one (CAS 1352209-43-8), molecular formula C8H3Cl2F3O and molecular weight 243.01 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-1-(4-chloro-3-fluorophenyl)-2,2-difluoroethan-1-one (C8H3Cl2F3O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-1-(4-chloro-3-fluorophenyl)-2,2-difluoroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C8H3Cl2F3O |
| Molecular Weight | 243.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |