3-Chloro-2-trifluoromethylbenzoyl chloride CAS 1228898-66-5
| CAS No. | 1228898-66-5 |
| Molecular Formula | C8H3Cl2F3O |
| Molecular Weight | 243.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-2-trifluoromethylbenzoyl chloride is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-2-trifluoromethylbenzoyl chloride (CAS 1228898-66-5) is a high-purity analytical reference standard with the molecular formula C8H3Cl2F3O and a molecular weight of 243.01 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-Chloro-2-trifluoromethylbenzoyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-2-trifluoromethylbenzoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3Cl2F3O |
| Molecular Weight | 243.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-(trifluoromethyl)benzoyl chloride (CAS 1092460-77-9)
- 2-Chloro-1-(4-chloro-3-fluorophenyl)-2,2-difluoroethan-1-one (CAS 1352209-43-8)
- 2-Chloro-1-(3-chloro-5-fluorophenyl)-2,2-difluoroethan-1-one (CAS 1352224-41-9)
- 4-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS 1735-55-3)
- 2-Chloro-3-(trifluoromethyl)benzoyl chloride (CAS 850156-39-7)
- 2-Chloro-6-(trifluoromethyl)benzoyl chloride (CAS 916420-44-5)
- 3-Chloro-5-(trifluoromethyl)benzoyl Chloride (CAS 886496-83-9)
- 4-Chloro-2-(trifluoromethyl)benzoyl Chloride (CAS 98187-13-4)
Recommended Standards
- 2,6-Dichloro-4-trifluoromethylbenzaldehyde (CAS 118754-52-2)
- 2-Bromo-5-nitrobenzo[d]oxazole (CAS 1246472-00-3)
- 6-Bromo-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (CAS 1112208-70-4)
- 1-(3,4-Dichlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 125733-43-9)
- 6-(4-Ethoxy-2-methylphenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1437485-79-4)
- Dimefuron (CAS 34205-21-5)
- 5-Cyano-4-(ethoxycarbonyl)-6-oxo-1,6-dihydropyridine-2-carboxylic acid (CAS 34086-91-4)
- 2'-Amino-[1,1'-biphenyl]-3-carbonitrile hydrochloride (CAS 1197237-84-5)
- 1-(3-Chloro-4-fluorophenyl)piperidine (CAS 1033201-89-6)
- (R)-4-(3-Aminobutyl)phenol (CAS 115548-15-7)
- Estradiol-3,17b-dibutyrate (CAS 63042-23-9)
- Methyl 4-bromo-1H-pyrazolo[3,4-c]pyridine-3-carboxylate (CAS 1363381-48-9)
- 2-Hydroxy-4-((tetrahydro-2H-pyran-2-yl)oxy)benzaldehyde (CAS 72041-59-9)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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