2-Chloro-2,2-difluoro-1-(3-fluoro-5-methylphenyl)ethan-1-one CAS 1352225-22-9
| CAS No. | 1352225-22-9 |
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-2,2-difluoro-1-(3-fluoro-5-methylphenyl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-Chloro-2,2-difluoro-1-(3-fluoro-5-methylphenyl)ethan-1-one (CAS 1352225-22-9), a certified reference material (molecular formula C9H6ClF3O, MW 222.59 g/mol) for analytical method development and quality control.
2-Chloro-2,2-difluoro-1-(3-fluoro-5-methylphenyl)ethan-1-one (C9H6ClF3O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1023812-01-2)
- 1-(5-Chloro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1214362-82-9)
- 1-(3-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-21-6)
- 1-(5-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-25-0)
- 4-Chloro-6-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine (CAS 1260666-44-1)
- 1-[3-chloro-4-(trifluoromethyl)phenyl]ethan-1-one (CAS 129322-80-1)
- 2’-Chloro-4’-(trifluoromethyl)acetophenone (CAS 129322-81-2)
- 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 129322-82-3)
Recommended Standards
- 2-Chloro-2,2-difluoro-1-(5-fluoro-2-methylphenyl)ethan-1-one (CAS 1352225-18-3)
- 4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine (CAS 137276-71-2)
- 2-Chloro-2,2-difluoro-1-(3-fluoro-4-methylphenyl)ethan-1-one (CAS 1352223-94-9)
- 4-Chloro-3-(trifluoromethyl)benzimidamide (CAS 1378867-56-1)
- [Platinum(II) (cyanide)(2,2"6,2"2-terpyridine)](hexafluorophosphate) (CAS 65599-60-2)
- 4,4',4''-((1E,1'E,1''E)-Benzene-1,3,5-triyltris(ethene-2,1-diyl))tribenzaldehyde (CAS 363622-54-2)
- [5-(4-Chlorophenyl)isoxazol-3-yl]methanol (CAS 81282-13-5)
- Methyl 2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinate (CAS 1622217-07-5)
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- Methyl 4-(3-(3-fluoro-4-methoxybenzoyl)-4-hydroxy-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618074-85-4)
- 4-Bromo-3,5-dichlorobenzyl Alcohol (CAS 1788545-31-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com