4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine CAS 137276-71-2
| CAS No. | 137276-71-2 |
| Molecular Formula | C8H6ClF3N2 |
| Molecular Weight | 222.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine.
CATO supplies 4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine (CAS 137276-71-2), a certified reference material (molecular formula C8H6ClF3N2, MW 222.59 g/mol) for analytical method development and quality control.
4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine (C8H6ClF3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2-cyclopropyl-6-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3N2 |
| Molecular Weight | 222.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1023812-01-2)
- 1-(5-Chloro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1214362-82-9)
- 1-(3-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-21-6)
- 1-(5-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-25-0)
- 4-Chloro-6-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine (CAS 1260666-44-1)
- 1-[3-chloro-4-(trifluoromethyl)phenyl]ethan-1-one (CAS 129322-80-1)
- 2’-Chloro-4’-(trifluoromethyl)acetophenone (CAS 129322-81-2)
- 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 129322-82-3)
Recommended Standards
- 2-Chloro-2,2-difluoro-1-(3-fluoro-5-methylphenyl)ethan-1-one (CAS 1352225-22-9)
- 4-Chloro-3-(trifluoromethyl)benzimidamide (CAS 1378867-56-1)
- 2-Chloro-2,2-difluoro-1-(5-fluoro-2-methylphenyl)ethan-1-one (CAS 1352225-18-3)
- 3-(Chloromethyl)-5-(trifluoromethyl)benzaldehyde (CAS 1393546-92-3)
- 6-(4-Fluorophenyl)-2-methylnicotinaldehyde (CAS 1242015-06-0)
- 1-Benzyl-3-(((tert-butyldimethylsilyl)oxy)methyl)piperidin-4-ol (CAS 934536-18-2)
- Methyl 7-fluoro-3-hydroxybenzo[b]thiophene-2-carboxylate (CAS 2091279-74-0)
- 6-(4-Isopropylphenyl)-2-phenylpyridazine-3(2H)-thione (CAS 378219-94-4)
- 4-(3-Iodophenoxy)pyridine (CAS 1249675-43-1)
- 4-(3-Nitro-4-(pyrrolidin-1-yl)phenyl)phthalazin-1-ol (CAS 672914-30-6)
- (1-Cyclopentyl-1h-pyrazol-5-yl)methanamine (CAS 1328640-76-1)
- 8-Chloro-2-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)-1,5-naphthyridine (CAS 2419129-92-1)
- 5-Chloro-2-(difluoromethyl)-1H-benzo[d]imidazole (CAS 91437-08-0)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
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