Methyl 3-(2-cyanophenyl)-5-fluorobenzoate CAS 1352318-48-9
| CAS No. | 1352318-48-9 |
| Molecular Formula | C15H10FNO2 |
| Molecular Weight | 255.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Methyl 3-(2-cyanophenyl)-5-fluorobenzoate (CAS 1352318-48-9), a certified reference material (molecular formula C15H10FNO2, MW 255.24 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 3-(2-cyanophenyl)-5-fluorobenzoate (C15H10FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Methyl 3-(2-cyanophenyl)-5-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10FNO2 |
| Molecular Weight | 255.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl-4-(2-cyanophenyl)-2-fluorobenzoate (CAS 1352317-81-7)
- Methyl 3-(4-cyanophenyl)-5-fluorobenzoate (CAS 1365271-88-0)
- Methyl 4-(4-cyanophenyl)-2-fluorobenzoate (CAS 1365272-59-8)
- Methyl 3-(3-cyanophenyl)-5-fluorobenzoate (CAS 1365272-83-8)
- Methyl 5-(4-cyanophenyl)-2-fluorobenzoate (CAS 1365272-84-9)
- Methyl 4-(3-cyanophenyl)-3-fluorobenzoate (CAS 1820642-19-0)
- 1-(3-Cyanophenyl)-3-isopropyl-1h-pyrazole-5-carboxylic acid (CAS 1012879-75-2)
- 1-(3-cyanophenyl)-5-propyl-1H-pyrazole-4-carboxylic acid (CAS 1153039-88-3)
Recommended Standards
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- Chlorohydridotris(triphenylphosphine)ruthenium(II) toluene adduct (CAS 55102-19-7)
- 2-Chloro-4-[chloro(difluoro)-methoxy]-1-fluoro-benzene (CAS 1404193-48-1)
- Ethyl 2-(2,5-difluorophenyl)-2,2-difluoroacetate (CAS 1343850-82-7)
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