Verapamil hydrochloride CAS 23313-68-0
| CAS No. | 23313-68-0 |
| Molecular Formula | C27H38N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Verapamil hydrochloride (CAS 23313-68-0), molecular formula C27H38N2O4HCl and molecular weight 491.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Verapamil hydrochloride (C27H38N2O4HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Verapamil hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H38N2O4 HCl |
| Molecular Weight | 491.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil Impurity 38 (CAS 114847-42-6)
- Verapamil D6 HCl (CAS 1185032-80-7)
- Verapamil-d7 Hydrochloride (CAS 1188265-55-5)
- Verapamil EP Impurity G (CAS 120-14-9)
- Verapamil EP Impurity J-D7 HCl (CAS 1216413-74-9)
- Verapamil EP Impurity B HCl (CAS 13078-76-7)
- (S)-(-)-Verapamil-d6 Hydrochloride (CAS 1329611-24-6)
Recommended Standards
- 1-Bromo-3-(3-chlorobut-3-en-1-yl)benzene (CAS 485320-30-7)
- Nbd-nystatin (CAS 96475-98-8)
- 4SL32YMY7B 543-94-2 Acetic acid, strontium salt Strontium acetate Strontium acetate hemihydrate Strontium di(acetate) Acetic acid, strontium salt (2:1) EINECS 208-854-8 NSC 75799 Strontium diacetate UNII-4SL32YMY7B (CAS 543-94-2)
- OPC 21268 (CAS 131631-89-5)
- 6-Fluoro-3-iodo-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one (CAS 145485-59-2)
- 5-(Chloromethyl)pyridin-2-amine hydrochloride (CAS 866561-43-5)
- 5-(4-(Dimethylamino)phenyl)-3-methyl-5-oxopentanoic acid (CAS 951893-04-2)
- 3,3-dimethyl-1-(methylsulfanyl)butan-2-one (CAS 39199-12-7)
- 4-(5-Fluoro-2-pyridinyl)benzenemethanol (CAS 1257426-54-2)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com