Efinaconazole Impurity 15 CAS 135270-07-4
| CAS No. | 135270-07-4 |
| Molecular Formula | C12H11F2N3O |
| Molecular Weight | 251.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Efinaconazole Impurity 15 (C12H11F2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Efinaconazole Impurity 15 (CAS 135270-07-4), a pharmacopoeial impurity reference standard (molecular formula C12H11F2N3O, MW 251.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Efinaconazole Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11F2N3O |
| Molecular Weight | 251.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Efinaconazole Standards
- Efinaconazole (2S,3R) epoxide, 98% (CAS 132563-77-0)
- Efinaconazole Impurity 14 (CAS 135270-10-9)
- Efinaconazole Impurity 16 (CAS CATO-C4X-124316)
- Efinaconazole Impurity 21 (CAS CATO-C4X-124321)
- Efinaconazole Impurity 30 (CAS 124627-86-7)
- Efinaconazole Impurity 47 (CAS CATO-C4X-124347)
- Efinaconazole Impurity 10 (CAS CATO-C4X-124310)
- Efinaconazole Impurity 6 (CAS CATO-C4X-12436)
Recommended Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole Impurity 195 (CAS CATO-C4X-1236195)
- Isavuconazole impurity 71 (CAS CATO-C4X-1236171)
- Isavuconazole Impurity 129 (CAS 2122222-15-3)
- Dopamine Impurity 49 (CAS CATO-C4X-151449)
- Darolutamide Impurity 30 (CAS CATO-C4X-310630)
- Zoledronic Acid Monohydrate EP Impurity D (CAS 22884-10-2)
- 2-Chloro-N-(3-(3-methyl-1H-indol-1-yl)propyl)acetamide (CAS 61985-40-8)
- Cefminox Sodium Heptahydrate (CAS 1351813-81-4)
- 3-Fluoro-4-methoxyphenethyl Alcohol (CAS 404-91-1)
- 4-Chlorocinnolin-6-ol (CAS 439085-78-6)
- 1-[2-(Thiomorpholin-4-yl)ethyl]imidazolidin-2-one (CAS 1331823-96-1)
- 7-Acetyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 84330-84-7)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com