2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid CAS 1352813-46-7
| CAS No. | 1352813-46-7 |
| Molecular Formula | C7H7BF2O3 |
| Molecular Weight | 187.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid (C7H7BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid (CAS 1352813-46-7) is a high-purity analytical reference standard with the molecular formula C7H7BF2O3 and a molecular weight of 187.94 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7BF2O3 |
| Molecular Weight | 187.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,3-Difluoro-4-(hydroxymethyl)phenylboronic acid (CAS 1315281-32-3)
- (2,4-Difluoro-5-methoxyphenyl)boronic acid (CAS 1395417-65-8)
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- (3,5-Difluoro-4-(hydroxymethyl)phenyl)boronic acid (CAS 917969-79-0)
Recommended Standards
- IODOACETIC ACID 13C2 (CAS 1173023-74-9)
- 4-Hydroxymethyl-2,6-difluorophenylboronic acid (CAS 1451393-60-4)
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- (2-(1,1-Difluoroethyl)pyrimidin-5-yl)boronic acid (CAS 1646268-29-2)
- 4-(Fluoromethyl)benzo[d]oxazol-2-ol (CAS 1806301-32-5)
- 593-79-3 YK0R6JKT6H Dimethylselenide Dimethyl selenide Methane, selenobis- (9CI) Methyl selenide (8CI) Selenide, dimethyl- 4-01-00-01288 (Beilstein Handbook Reference) BRN 1696848 Dimethylselenium EINECS 209-807-4 Methyl selenium HSDB 7900 UNII-YK0R6JKT6H Methyl selenide (CAS 593-79-3)
- 4-[(2-methoxyethyl)amino]benzoic acid (CAS 855199-07-4)
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- (3S,4R)-1-[(tert-Butoxy)carbonyl]-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pyrrolidine-3-carboxylic acid (CAS 346610-79-5)
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- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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