(2,4-Difluoro-3-methoxyphenyl)boronic acid CAS 406482-18-6
| CAS No. | 406482-18-6 |
| Molecular Formula | C7H7BF2O3 |
| Molecular Weight | 187.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2,4-Difluoro-3-methoxyphenyl)boronic acid.
(2,4-Difluoro-3-methoxyphenyl)boronic acid (CAS 406482-18-6), molecular formula C7H7BF2O3 and molecular weight 187.94 g/mol, is a CATO reference standard with documented purity and traceability.
(2,4-Difluoro-3-methoxyphenyl)boronic acid (C7H7BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2,4-Difluoro-3-methoxyphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BF2O3 |
| Molecular Weight | 187.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,3-Difluoro-4-(hydroxymethyl)phenylboronic acid (CAS 1315281-32-3)
- 2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid (CAS 1352813-46-7)
- (2,4-Difluoro-5-methoxyphenyl)boronic acid (CAS 1395417-65-8)
- (2,3-Difluoro-4-methoxyphenyl)boronic acid (CAS 170981-41-6)
- 2,4-Difluoro-6-methoxyphenylboronic Acid (CAS 1808997-86-5)
- (3,4-Difluoro-2-methoxyphenyl)boronic acid (CAS 905583-06-4)
- (3,4-Difluoro-5-methoxyphenyl)boronic acid (CAS 925910-42-5)
- (3,5-Difluoro-4-(hydroxymethyl)phenyl)boronic acid (CAS 917969-79-0)
Recommended Standards
- (2-(Difluoromethoxy)phenyl)boronic acid (CAS 947533-11-1)
- (2-(1,1-Difluoroethyl)pyrimidin-5-yl)boronic acid (CAS 1646268-29-2)
- (3,6-Difluoro-2-methoxyphenyl)boronic acid (CAS 919355-30-9)
- 4-Hydroxymethyl-2,6-difluorophenylboronic acid (CAS 1451393-60-4)
- (4R,5S,6R)-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-ol (CAS 160549-11-1)
- Ethyl 2,6-dimethyl-4-oxocyclohexanecarboxylate (CAS 36714-68-8)
- 3-(Trifluoromethoxy)cyclohexan-1-one (CAS 2231674-23-8)
- 4-(2-Aminoethoxy)benzamide (CAS 50714-69-7)
- (S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate (CAS 24277-38-1)
- 6-(3,3,3-Trifluoropropoxy)pyridin-2-amine (CAS 1551521-44-8)
- 8-Bromo-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 5055-01-6)
- methyl 3-fluoro-5-hydroxypyridine-2-carboxylate (CAS 1256836-96-0)
- tert-butyl 1,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4’-oxane]-5-carboxylate (CAS 1955557-23-9)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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