N-(3-Bromo-2-chloro-5-fluorophenyl)pivalamide CAS 1353575-26-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1353575-26-4
Molecular FormulaC11H12BrClFNO
Molecular Weight308.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-Bromo-2-chloro-5-fluorophenyl)pivalamide CAS 1353575-26-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 308.57 g/mol gives N-(3-Bromo-2-chloro-5-fluorophenyl)pivalamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(3-Bromo-2-chloro-5-fluorophenyl)pivalamide (CAS 1353575-26-4), a certified reference material (molecular formula C11H12BrClFNO, MW 308.57 g/mol) for analytical method development and quality control.

The molecular framework of N-(3-Bromo-2-chloro-5-fluorophenyl)pivalamide (C11H12BrClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H12BrClFNO
Molecular Weight308.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1

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