(S)-N-((1-(2-Chloroacetyl)pyrrolidin-2-yl)methyl)-N-isopropylacetamide CAS 1354008-22-2
| CAS No. | 1354008-22-2 |
| Molecular Formula | C12H21ClN2O2 |
| Molecular Weight | 260.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (S)-N-((1-(2-Chloroacetyl)pyrrolidin-2-yl)methyl)-N-isopropylacetamide (C12H21ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies (S)-N-((1-(2-Chloroacetyl)pyrrolidin-2-yl)methyl)-N-isopropylacetamide (CAS 1354008-22-2), a certified reference material (molecular formula C12H21ClN2O2, MW 260.76 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (S)-N-((1-(2-Chloroacetyl)pyrrolidin-2-yl)methyl)-N-isopropylacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H21ClN2O2 |
| Molecular Weight | 260.76 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-[(R)-1-(2-Chloro-acetyl)-piperidin-3-yl]-N-ethyl-acetamide (CAS 1354001-49-2)
- N-benzyl-1-(5-(chloromethyl)-4-methylpyridin-2-yl)methanamine (CAS 1355191-94-4)
- N-[(S)-1-(2-Chloro-acetyl)-pyrrolidin-2-ylmethyl]-N-ethyl-acetamide (CAS 1353997-03-1)
- 2,7-Dimethyl-1-benzothiophene-3-sulfonyl chloride (CAS 1384431-09-7)
- Tert-butyl 2-oxa-7-azaspiro[4.4]Nonane-7-carboxylate (CAS 1824270-71-4)
- (R)-1-Benzyl-5-oxopyrrolidine-3-carboxylicacid (CAS 1217736-39-4)
- 1-(4-Bromophenyl)-1-cyclopropylethanol (CAS 56041-75-9)
- 2-Nonanone, 5-ethyl- (CAS 5440-89-1)
- Ethyl 2-[3-(difluoromethyl)-1H-pyrazol-1-yl]butanoate (CAS 1823442-43-8)
- Dimethyl 2-(3-amino-2-(methoxycarbonyl)phenyl)malonate (CAS CATO-C3D-3124)
- 2-(1-Methylpiperidin-3-yl)acetaldehyde (CAS 881841-76-5)
- 2-(4h-1,2,4-Triazol-3-yl)acetonitrile (CAS 28824-81-9)
- Nebivolol Impurity 93 (CAS CATO-C4X-196893)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com