Nebivolol Impurity 93 CAS CATO-C4X-196893
| CAS No. | CATO-C4X-196893 |
| Molecular Formula | C40H44ClF2N3O8 |
| Molecular Weight | 768.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 768.24 g/mol gives Nebivolol Impurity 93 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nebivolol Impurity 93 (CAS CATO-C4X-196893) is a certified pharmaceutical impurity reference standard with the molecular formula C40H44ClF2N3O8 and a molecular weight of 768.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Nebivolol Impurity 93 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 768.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H44ClF2N3O8 |
| Molecular Weight | 768.24 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Nebivolol Standards
- Nebivolol Impurity 94 (CAS CATO-C4X-196894)
- Nebivolol Impurity 95 (CAS CATO-C4X-196895)
- Nebivolol Impurity 98 (CAS CATO-C4X-196898)
- Nebivolol Impurity 90 (CAS CATO-C4X-196890)
- Nebivolol Impurity 92 (CAS CATO-C4X-196892)
- Nebivolol Impurity 101 (CAS CATO-C4X-1968101)
- Nebivolol Impurity 96 (CAS CATO-C4X-196896)
- Nebivolol Impurity 100 (CAS CATO-C4X-1968100)
Recommended Standards
- Cefdinir Impurity 82 (CAS 2489663-67-2)
- (2R)-3-(hexadecyloxy)-2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxy}propyl 2-(trimethylazaniumyl)ethyl phosphate 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine 1-O-hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine 86288-11-1 CHEBI:55430 PC(O-16:0/20:4(5Z,8Z,11Z,14Z)) (CAS 86288-11-1)
- Ceftazidime impurity 119 (CAS CATO-C4X-1212119)
- 5Z,8Z,11Z,14Z-eicosatetraenoicacid,(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethylester 61216-62-4 (CAS 61216-62-4)
- Sofosbuvir Impurity 89 (CAS CATO-C4X-105289)
- Dimefline Impurity 2 (CAS CATO-C4X-33512)
- Niraparib Impurity N9 (CAS 1203683-54-8)
- Perfluoroanthracene (CAS 1580-19-4)
- (2,2-dimethylpropyl)(2,2,2-trifluoroethyl)amine (CAS 1183413-67-3)
- 3-Fluoro-5-(4-methylpyridin-3-yl)aniline (CAS 791644-60-5)
- (2-(Benzyloxy)-5-fluorophenyl)methanamine (CAS 1096895-23-6)
- 3-(3-Chlorophenyl)-5-((4-fluorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 874792-62-8)
- N-Cyclopentyl-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine (CAS 113181-12-7)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
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