(S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide CAS 1354020-60-2
| CAS No. | 1354020-60-2 |
| Molecular Formula | C10H14ClN3OS |
| Molecular Weight | 259.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.76 g/mol gives (S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide (CAS 1354020-60-2), molecular formula C10H14ClN3OS and molecular weight 259.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide (C10H14ClN3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14ClN3OS |
| Molecular Weight | 259.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 1-{4-[(2-chloro-1,3-thiazol-5-yl)methyl]piperazin-1-yl}ethan-1-one (CAS 865660-24-8)
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