1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol CAS 1261229-47-3
| CAS No. | 1261229-47-3 |
| Molecular Formula | C10H14ClN3OS |
| Molecular Weight | 259.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol.
1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol (CAS 1261229-47-3) is a high-purity analytical reference standard with the molecular formula C10H14ClN3OS and a molecular weight of 259.76 g/mol.
The molecular framework of 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol (C10H14ClN3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14ClN3OS |
| Molecular Weight | 259.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(6-Chloro-2-(methylthio)pyrimidin-4-yl)piperidin-4-ol (CAS 1261231-33-7)
- 1-{4-[(2-chloro-1,3-thiazol-5-yl)methyl]piperazin-1-yl}ethan-1-one (CAS 865660-24-8)
- 2-Chloro-N-(5-(cyclopentylmethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 908528-65-4)
- 2-Chloro-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 83390-45-8)
- 3-Chloro-2-methyl-N-(2-methylphenethyl)aniline (CAS 1040688-34-3)
- N-Chloro-2,2,6,6-tetramethyl-4-piperidyl Methacrylate (CAS 1126272-77-2)
- 6-Chloro-2-methylquinoline-3-carboxylic acid ethyl ester (CAS 114858-39-8)
- 2-Chloro-4-[2-(methylsulfanyl)phenyl]benzonitrile (CAS 1237083-91-8)
Recommended Standards
- tert-Butyl (5-chloro-2-mercaptophenyl)carbamate (CAS 2228366-71-8)
- 5-Chloro-3-(phenylthio)-1H-indole (CAS 227803-35-2)
- (S)-2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-cyclopropylpropanamide (CAS 1354020-60-2)
- 5-Chloro-2-(phenylthio)-1H-indole (CAS 227803-36-3)
- (3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-1-pivaloylpyrrolidin-2-one (CAS 1038924-66-1)
- 5-Hydroxy Bromantane (CAS 560070-28-2)
- Prothipendyl-d6 Hydrochloride (CAS 1346604-67-8)
- 2-(6-(Phenylamino)pyridin-3-yl)ethanol (CAS 1355219-77-0)
- n-[(4-methoxyphenyl)methyl]prop-2-enamide (CAS 70875-53-5)
- Tropicamide EP Impurity B HCL (CAS CATO-C4X-21505)
- 3-Ethyl-2-hydroxypentanoic acid (CAS 301221-97-6)
- 3-(2,4-Dimethylphenyl)pyridin-4-amine (CAS 1343847-73-3)
- (3Z)-3-[(Furan-2-yl)methylidene]piperazine-2,5-dione (CAS 155527-33-6)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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