5-Hydroxy-4-(2-methoxy-5-(trifluoromethyl)phenyl)-5-methylfuran-2(5H)-one CAS 1354819-34-3
| CAS No. | 1354819-34-3 |
| Molecular Formula | C13H11F3O4 |
| Molecular Weight | 288.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Hydroxy-4-(2-methoxy-5-(trifluoromethyl)phenyl)-5-methylfuran-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Hydroxy-4-(2-methoxy-5-(trifluoromethyl)phenyl)-5-methylfuran-2(5H)-one (CAS 1354819-34-3), molecular formula C13H11F3O4 and molecular weight 288.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Hydroxy-4-(2-methoxy-5-(trifluoromethyl)phenyl)-5-methylfuran-2(5H)-one (C13H11F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11F3O4 |
| Molecular Weight | 288.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 4-Hydroxy-6-methyl-3-nitro-2H-pyrano[3,2-c]quinoline-2,5(6H)-dione (CAS 161185-52-0)
- (4-Hydroxy-3-nitrophenyl)(3-nitrophenyl)methanone (CAS 37567-45-6)
- Methyl 2-(5-hydroxy-1-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-pyrazol-3-yl)acetate (CAS 1956340-78-5)
- (E)-4-hydroxy-N-((methoxyimino)methyl)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxamide (CAS 339015-81-5)
- 2-(2-Hydroxy-4-nitrophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (CAS 774189-08-1)
- 2-Hydroxy-n-(2-methoxy-4-nitrophenyl)benzamide (CAS 73454-94-1)
- 2-Hydroxy-n-(4-methoxy-2-nitrophenyl)benzamide (CAS 73454-95-2)
- 4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (CAS 2244568-06-5)
Recommended Standards
- N-(5-Oxopyrrolidin-3-yl)-4-(trifluoromethoxy)benzamide (CAS 1351642-67-5)
- Lenacapavir Impurity N1 (CAS 1417983-07-3)
- Methyl 2-methyl-4-(2,2,2-trifluoroethoxy)benzofuran-6-carboxylate (CAS 1291490-37-3)
- 3-(Trifluoromethyl)benzyl (R)-5-oxotetrahydrofuran-2-carboxylate (CAS 1445700-01-5)
- 2-(4-Fluorobenzyl)pent-4-enoic acid (CAS 18622-66-7)
- 2-((3-(4-Chlorophenoxy)-4-oxo-4h-chromen-7-yl)oxy)acetic acid (CAS 315234-25-4)
- 2-(Cyclopropylmethoxy)-5-iodopyridine (CAS 902837-53-0)
- Parasin I (CAS 219552-69-9)
- 5-(Chloromethyl)-2-phenylpyridine (CAS 5229-40-3)
- 2-({4-[(difluoromethyl)sulfanyl]phenyl}amino)benzoic acid (CAS 51679-50-6)
- 5-(Dimethylamino)-2-methylisoindoline-1,3-dione (CAS 2307-01-9)
- 287100-67-8 D-Glucose-1,6-13C2 Dextrose-1,6-13C2 Labeled Glucose (CAS 287100-67-8)
- 2-(4-Fluoro-5-methylpyridin-3-yl)ethan-1-amine (CAS 1393544-14-3)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com