Remdesivir Impurity 8 CAS 1354823-36-1
| CAS No. | 1354823-36-1 |
| Molecular Formula | C21H27N2O7P |
| Molecular Weight | 450.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Remdesivir Impurity 8.
As a process- or degradation-related impurity, Remdesivir Impurity 8 (CAS 1354823-36-1, C21H27N2O7P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Remdesivir Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 450.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Remdesivir Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27N2O7P |
| Molecular Weight | 450.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Remdesivir Standards
- Remdesivir Impurity 22 (CAS 2096985-18-9)
- Remdesivir Impurity 23 (CAS 2093124-22-0)
- Remdesivir Impurity 34 (CAS 1354823-37-2)
- Remdesivir Impurity 7 (CAS 1439900-56-7)
- Remdesivir Impurity 32 (CAS CATO-C4X-210032)
- Remdesivir Impurity 15 (CAS CATO-C4X-210015)
- Remdesivir Impurity 14 (CAS CATO-C4X-210014)
- Remdesivir Impurity 36 (CAS CATO-C4X-210036)
Recommended Standards
- 1,1-[(1,1-Dimethylethyl)[[(1R,2E)-1-ethyl-3-iodo-2-propen-1-yl]oxy]silylene]bis-benzene (CAS 1309610-39-6)
- 5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 957040-67-4)
- Methyl 4-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzoate (CAS 317833-48-0)
- S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine (CAS 41094-07-9)
- Memantine Impurity 61 (CAS 111035-07-5)
- Nefopam impurity 25 (CAS CATO-C4X-283725)
- Bupropion Morpholinol Impurity (HCl Salt) (CAS 106083-71-0)
- 1-(2-Chlorophenyl)-N-methyl-3-(pyrrolidin-1-yl)propan-1-aminehydrochloride (CAS 1956335-24-2)
- 1-(1,8-Naphthyridin-4-yl)ethan-1-one (CAS 893566-24-0)
- N,N,N-Trimethyl-1-(pyridin-4-yl)methanaminium iodide (CAS 20863-50-7)
- 2-Bromo-4-(tert-butyl)-6-nitroaniline (CAS 1027356-55-3)
- Ethyl 2-[8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]benzenecarboxylate (CAS 900015-41-0)
- 5-(1-Hydroxyethyl)-1,3-phenylene diacetate (CAS 847862-83-3)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com