5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile CAS 957040-67-4
| CAS No. | 957040-67-4 |
| Molecular Formula | C25H18F4N4 |
| Molecular Weight | 450.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile (C25H18F4N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 957040-67-4), a certified reference material (molecular formula C25H18F4N4, MW 450.43 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H18F4N4 |
| Molecular Weight | 450.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related bis Standards
- 1-(2,4-Difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-08-5)
- 1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-10-9)
- 2-(3,4-Difluorophenyl)-4-((3-methylbut-2-en-1-yl)oxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 890306-94-2)
- 2-(3,4-Difluorophenyl)-4-((3-methylbut-3-en-1-yl)oxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 890306-92-0)
- N-(2,4-Difluorophenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775421-30-1)
- N-(2,5-Difluorophenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775510-60-5)
- 8-(2,6-Difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 444606-18-2)
- N-(2,4-difluorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040633-88-2)
Recommended Standards
- 1,1-[(1,1-Dimethylethyl)[[(1R,2E)-1-ethyl-3-iodo-2-propen-1-yl]oxy]silylene]bis-benzene (CAS 1309610-39-6)
- Methyl 4-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzoate (CAS 317833-48-0)
- Remdesivir Impurity 8 (CAS 1354823-36-1)
- S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine (CAS 41094-07-9)
- 2-((tert-Butoxycarbonyl)amino)-3,6-dichlorobenzoic acid (CAS 1697677-00-1)
- 2-[(3-fluorophenyl)amino]acetic acid hydrochloride (CAS 1306603-97-3)
- 4-Hydroxy-2-(hydroxymethyl)-5-methylfuran-3(2H)-one (CAS 17678-20-5)
- 2-[(4-Hydroxy-5-methoxypyrimidin-2-yl)sulfanyl]acetic acid (CAS 90151-22-7)
- (2-Bromo-4-methoxyphenyl)hydrazine (CAS 299165-34-7)
- 2-Hydroxy-1H-benzo[d]imidazole-4-sulfonamide (CAS 1378260-67-3)
- 4-Amino-3-fluorobenzaldehyde (CAS 146019-47-8)
- 7-amino-3H-quinazolin-4-one (CAS 90004-09-4)
- 1,1-Oxydi-2-Propanol(Mixture of isomers) (CAS 110-98-5)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com