4,4-Bis(trifluoromethyl)pyrrolidine-2-carboxylic acid CAS 1354950-53-0
| CAS No. | 1354950-53-0 |
| Molecular Formula | C7H7F6NO2 |
| Molecular Weight | 251.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4,4-Bis(trifluoromethyl)pyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4,4-Bis(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1354950-53-0), molecular formula C7H7F6NO2 and molecular weight 251.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,4-Bis(trifluoromethyl)pyrrolidine-2-carboxylic acid (C7H7F6NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7F6NO2 |
| Molecular Weight | 251.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 4,4-Bis(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1251924-62-5)
- 1-((Trifluoromethyl)sulfonyl)-1H-benzo[d][1,2,3]triazole (CAS 117632-84-5)
- 6-Methyl-2-(trifluoromethyl)thiazolo[3,2-b][1,2,4]triazole-5-carboxylic acid (CAS 264880-53-7)
- 4-(4-(Trifluoromethyl)phenyl)picolinaldehyde (CAS 1005189-47-8)
- 6-(2-(Trifluoromethyl)phenyl)picolinaldehyde (CAS 112432-96-9)
- 2-(4-(Trifluoromethyl)phenyl)isonicotinaldehyde (CAS 1198794-20-5)
- 2-Methyl-5-(4-trifluoromethyl-phenyl)-furan-3-carbonitrile (CAS 1858242-19-9)
- 2-(Trifluoromethyl)-10H-phenoxazine (CAS 2069-57-0)
Recommended Standards
- 4-Fluoro-2-(2,2,2-trifluoroacetamido)benzoic acid (CAS 128992-67-6)
- 6-Chloro-2,3-dihydro-1H-indene-5-sulfonyl chloride (CAS 1541069-38-8)
- 3-Fluoro-4-(2,2,2-trifluoroacetamido)benzoic acid (CAS 1284288-25-0)
- Methyl 2,6-Dichloro-4-(methylthio)benzoate (CAS 1823359-63-2)
- 4-(Difluoromethyl)-3-(fluoromethyl)-5-methoxypyridine (CAS 1806767-70-3)
- Ethyl 2-(3,5-dichlorophenoxy)acetate (CAS 119024-29-2)
- cis-4-Amino-4-methylcyclohexanol hydrochloride (CAS 923598-04-3)
- 4,8-dichloroimidazo[1,5-a]quinoxaline (CAS 1334331-43-9)
- Ivermectin EP Impurity I (4S-Isomer) (CAS CATO-C4X-19829)
- Octyl 3-6-di-O-(α-D-mannopyranosyl)-β-D-mannopyranoside (CAS 140147-36-0)
- 6-(2,2-Dimethoxyethyl)-9H-purine (CAS 920503-29-3)
- 6'-Bromo-2H-[1,2'-bipyridin]-2-one (CAS 959237-86-6)
- 4-(Dihexylamino)benzaldehyde (CAS 90133-80-5)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com