Ivermectin EP Impurity I (4S-Isomer) CAS CATO-C4X-19829
| CAS No. | CATO-C4X-19829 |
| Molecular Formula | C48H74O14 |
| Molecular Weight | 875.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ivermectin EP Impurity I (4S-Isomer) (CAS CATO-C4X-19829, C48H74O14) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ivermectin EP Impurity I (4S-Isomer) (C48H74O14) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H74O14 |
| Molecular Weight | 875.09 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ivermectin Standards
- Ivermectin EP Impurity F (CAS CATO-C4X-198213)
- Ivermectin EP Impurity I(Mixture of Diastereomers) (CAS 1135339-49-9)
- Ivermectin impurity 22 (CAS CATO-C4X-198222)
- Ivermectin B1a (CAS 71827-03-7)
- Ivermectin EP Impurity A (CAS 65195-55-3)
- Ivermectin EP Impurity K (CAS 74567-01-4)
- Ivermectin EP Impurity D (CAS 102190-55-6)
- Ivermectin B1b (CAS 70209-81-3)
Recommended Standards
- Carfilzomib Impurity 89 (CAS CATO-C4X-102289)
- Carfilzomib Impurity 93 (CAS CATO-C4X-102293)
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- (3-Bromo-2,6-dimethoxypyridin-4-yl)bis(3,5-dimethylphenyl)phosphine oxide (CAS 442686-32-0)
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- Posaconazole Impurity 144 (CAS 2243785-81-9)
- Liraglutide Impurity 5 TFA Salt (CAS CATO-C4X-19925)
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