2-Hydroxy-2-(5-methylthiazol-2-yl)acetonitrile CAS 1355223-99-2
| CAS No. | 1355223-99-2 |
| Molecular Formula | C6H6N2OS |
| Molecular Weight | 154.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 154.19 g/mol gives 2-Hydroxy-2-(5-methylthiazol-2-yl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Hydroxy-2-(5-methylthiazol-2-yl)acetonitrile (CAS 1355223-99-2), a certified reference material (molecular formula C6H6N2OS, MW 154.19 g/mol) for analytical method development and quality control.
The molecular framework of 2-Hydroxy-2-(5-methylthiazol-2-yl)acetonitrile (C6H6N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Hydroxy-2-(5-methylthiazol-2-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6N2OS |
| Molecular Weight | 154.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- 3-Hydroxy-3-(1,3-thiazol-2-yl)propanenitrile (CAS 1094405-17-0)
- 2-Hydroxy-2-(2-methylthiazol-5-yl)acetonitrile (CAS 113732-80-2)
- 4-Hydroxy-3-mercaptobenzaldehyde (CAS 166590-53-0)
- 4-Hydroxy-5-methyl-2-(methylthio)pyrimidine (CAS 20651-30-3)
- 2-Hydroxy-1-propyl Methanesulfonate (CAS 113391-95-0)
- 2-Hydroxy-4,5,6,7-tetrahydro-2H-indazol-3(3aH)-one (CAS 107398-92-5)
- 6-Hydroxy-2-isopropylpyrimidin-4(3H)-one (CAS 1197-04-2)
- DL-2-Hydroxy-4-(methylthio)butanoic Acid-13C4DISCONTINUED, see H555660 (CAS 1215556-82-3)
Recommended Standards
- (4H-Pyrrolo[2,3-d]thiazol-5-yl)methanol (CAS 1327366-68-6)
- 1-(Thiophen-3-yl)propane-1,2-dione (CAS 13678-78-9)
- Imidazo[2,1-b]thiazol-5-ylmethanol (CAS 130182-37-5)
- 6,7-Dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 139218-70-5)
- 4-(Cyclopentyloxy)-2-hydroxybenzonitrile (CAS 1352503-84-4)
- 1-Allyl-3-(2-(2,4-dioxothiazolidin-3-yl)cyclohexyl)urea (CAS 1207040-86-5)
- 1-(4-Methylbenzyl)-1h-imidazole-2-thiol (CAS 105764-00-9)
- 4-(2-Methoxyphenyl)butan-1-amine (CAS 154585-02-1)
- Methyl 2-amino-4-(3,4-dimethylphenyl)thiophene-3-carboxylate (CAS 350990-08-8)
- 6-Chloro-2-(chloromethyl)quinazoline (CAS 1935563-21-5)
- 2-amino-N-(2-hydroxyethyl)benzamide (CAS 49667-81-4)
- Heveaflavone (CAS 23132-13-0)
- 4-Bromo-2-fluoroanisole (CAS 2357-52-0)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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