6-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methylnicotinic acid CAS 1355224-80-4
| CAS No. | 1355224-80-4 |
| Molecular Formula | C16H16N2O2 |
| Molecular Weight | 268.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 6-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methylnicotinic acid (CAS 1355224-80-4), a certified reference material (molecular formula C16H16N2O2, MW 268.31 g/mol) for analytical method development and quality control.
6-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methylnicotinic acid (C16H16N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16N2O2 |
| Molecular Weight | 268.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Dihydroisoquinolin Standards
- 6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylnicotinic acid (CAS 1355200-34-8)
- 6-(3,4-Dihydroisoquinolin-2(1H)-yl)-5-methylnicotinic acid (CAS 1355201-52-3)
- Methyl 6-(3,4-dihydroisoquinolin-2(1H)-yl)nicotinate (CAS 1355201-90-9)
- 1-(6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylpyridin-3-yl)ethanol (CAS 1355204-31-7)
- 3-(3,4-Dihydroisoquinolin-2(1H)-yl)-1-(pyridin-2-yl)propan-1-ol (CAS 439111-00-9)
- 1-(6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylpyridin-3-yl)ethan-1-amine (CAS 1355223-47-0)
- 1-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methylpyrimidin-5-yl]ethanone (CAS 903475-61-6)
- 2-(3,4-Dihydroisoquinolin-2(1H)-yl)-4-methylpyrimidine-5-carboxylic acid (CAS 1017485-42-5)
Recommended Standards
- (6-Morpholinopyridin-3-yl)(phenyl)methanone (CAS 1355207-85-0)
- Methyl 6-(indolin-1-yl)-5-methylnicotinate (CAS 1355227-25-6)
- 6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid (CAS 1355236-18-8)
- 6-(3,4-Dihydroquinolin-1(2H)-yl)-5-methylnicotinic acid (CAS 1355236-82-6)
- Ethyl 5-methoxy-2-nitrobenzoate (CAS 10399-67-4)
- (E)-3-(5-(4-chlorophenyl)furan-2-yl)-2-(phenylsulfonyl)acrylonitrile (CAS 64251-72-5)
- Methyl 4-methyl-3-(2-oxoimidazolidin-1-yl)benzoate (CAS 1209678-87-4)
- 2-Chloro-7,7-dimethyl-1,6,7,8-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one (CAS 1383777-81-8)
- (S)-Methyl 2-(3-(4-hydroxyphenyl)acrylamido)-3-phenylpropanoate (CAS 615264-52-3)
- 5-Cyclopropoxy-N-methyl-4-(trifluoromethyl)picolinamide (CAS 1243449-22-0)
- Landiolol Impurity 125 (CAS CATO-C4X-2621125)
- 3-Amino-3-(2-methoxyphenyl)-2,2-dimethyl-1-propanol (CAS 1337653-34-5)
- (R)-2-Chloro-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one (CAS 2344823-08-9)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com