6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid CAS 1355236-18-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid.

CATO supplies 6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid (CAS 1355236-18-8), a certified reference material (molecular formula C16H16N2O2, MW 268.31 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(3,4-Dihydroquinolin-1(2H)-yl)-2-methylnicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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