2-Chloro-4-(4-chloro-2-methoxyphenyl)benzonitrile CAS 1355248-21-3
| CAS No. | 1355248-21-3 |
| Molecular Formula | C14H9Cl2NO |
| Molecular Weight | 278.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-(4-chloro-2-methoxyphenyl)benzonitrile (CAS 1355248-21-3), molecular formula C14H9Cl2NO and molecular weight 278.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4-(4-chloro-2-methoxyphenyl)benzonitrile (C14H9Cl2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-4-(4-chloro-2-methoxyphenyl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl2NO |
| Molecular Weight | 278.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-(5-chloro-2,4-dimethoxyphenyl)propanamide (CAS 1016757-52-0)
- 6-Chloro-3-(4-chlorophenyl)-2H-1,4-benzoxazine (CAS 112030-47-4)
- 2-Chloro-5-[(4-chloro-3-fluorophenoxy)methyl]-1,3-thiazole (CAS 338393-41-2)
- 2-Chloro-N-(4-chloro-2,5-dimethoxyphenyl)-propanamide (CAS 956576-39-9)
- 7-Chloro-3-(2-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1019918-60-5)
- 3-Chloro-6-(3-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 866132-38-9)
- 3-Chloro-6-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 439107-64-9)
- 5-Chloro-2-(6-chloropyridin-3-yl)-1-methyl-1H-benzo[d]imidazole (CAS 400076-01-9)
Recommended Standards
- Loratadine Impurity 7 (CAS 133330-61-7)
- 1-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-one (CAS 1365803-10-6)
- 4-(Benzyloxy)-3,5-dichlorobenzonitrile (CAS 120110-61-4)
- 2-(3-Cyclopropoxy-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1416367-15-1)
- Resolve-Al<SUP>™</SUP> EuFOD (CAS 17631-68-4)
- 4-Methyl-N-(pyrimidin-5-ylmethyl)pyridin-3-amine (CAS 1339368-28-3)
- 1-(4-Fluorophenyl)-3-isopropoxypropan-2-amine (CAS 1507286-16-9)
- Indapamide Impurity 6 (CAS 2455-92-7)
- (S)-2-(3-(((2,4-Diaminoquinazolin-6-yl)methyl)amino)benzamido)pentanedioic acid (CAS 29746-12-1)
- Nicorandil Impurity 43 (CAS 1570-45-2)
- 4-Decylphenol (CAS 2985-57-1)
- 5-Methylbenzene-1,2,3-triol (CAS 609-25-6)
- 2-(4-Chlorophenyl)-1-ethyl-1H-indole (CAS 131197-07-4)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
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