1-Fluoro-2-methoxy-4-(3-nitrophenyl)benzene CAS 1355248-22-4
| CAS No. | 1355248-22-4 |
| Molecular Formula | C13H10FNO3 |
| Molecular Weight | 247.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Fluoro-2-methoxy-4-(3-nitrophenyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Fluoro-2-methoxy-4-(3-nitrophenyl)benzene (CAS 1355248-22-4), molecular formula C13H10FNO3 and molecular weight 247.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Fluoro-2-methoxy-4-(3-nitrophenyl)benzene (C13H10FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H10FNO3 |
| Molecular Weight | 247.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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- 3-Fluoro-4-(2-hydroxyphenoxy)benzamide (CAS 1184066-84-9)
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- 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid (CAS 1261934-09-1)
- 6-(4-Fluoro-3-methoxyphenyl)picolinic acid (CAS 1261977-99-4)
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- Methyl 6-(3-fluoro-5-hydroxyphenyl)nicotinate (CAS 1417792-34-7)
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