Sulfamethoxazole EP Impurity B CAS 135529-16-7
| CAS No. | 135529-16-7 |
| Molecular Formula | C16H16N4O5S2 |
| Molecular Weight | 408.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sulfamethoxazole EP Impurity B.
As a process- or degradation-related impurity, Sulfamethoxazole EP Impurity B (CAS 135529-16-7, C16H16N4O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sulfamethoxazole EP Impurity B (C16H16N4O5S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sulfamethoxazole EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O5S2 |
| Molecular Weight | 408.45 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Sulfamethoxazole Standards
- Sulfamethoxazole Impurity 11 (CAS CATO-C4X-190911)
- Sulfamethoxazole N4-glucoside (alpha/beta mixture) (CAS 119691-75-7)
- Sulfamethoxazole b-D-Glucuronide (CAS 14365-52-7)
- Sulfamethoxazole EP Impurity A (CAS 21312-10-7)
- Sulfamethoxazole Impurity 9 (CAS 18607-98-2)
- Sulfamethoxazole-13C6 (CAS 1196157-90-0)
- Sulfamethoxazole-d4 (CAS 1020719-86-1)
- Sulfamethoxazole EP Impurity F (CAS 17103-52-5)
Recommended Standards
- Ethyl 5-(2-(2-(diethylamino)-2-oxoacetyl)-1H-pyrrol-1-yl)-1-phenyl-1H-pyrazole-4-carboxylate (CAS 477709-21-0)
- Melphalan Impurity 34 (CAS CATO-C4X-198834)
- Dicyclohexylphosphinic acid (CAS 832-39-3)
- Roxadustat Impurity 13 (CAS CATO-C4X-221313)
- Ticagrelor Impurity 108 (CAS 2417798-14-0)
- Fasudil Impurity 21 (CAS CATO-C4X-136521)
- Crizotinib Impurity 9 (CAS 1448326-33-7)
- Piracetam Impurity 50 (CAS CATO-C4X-123550)
- 7-Amino-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 863305-83-3)
- (E)-Cinnamyl 3-methylbutanoate (CAS 69121-78-4)
- Cyclooctylmethanamine hydrochloride (CAS 1209904-16-4)
- (4-bromo-3-fluorophenyl)methanesulfonamide (CAS 1187202-27-2)
- N,N-Diethyl-4-methyl-3-nitroaniline (CAS 810662-45-4)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com