Fasudil Impurity 21 CAS CATO-C4X-136521
| CAS No. | CATO-C4X-136521 |
| Molecular Formula | C19H25BrN2O4S2 |
| Molecular Weight | 489.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fasudil Impurity 21.
CATO supplies Fasudil Impurity 21 (CAS CATO-C4X-136521), a pharmacopoeial impurity reference standard (molecular formula C19H25BrN2O4S2, MW 489.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Fasudil Impurity 21 (C19H25BrN2O4S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H25BrN2O4S2 |
| Molecular Weight | 489.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Fasudil Standards
- Fasudil Dimer Impurity (CAS 1337967-93-7)
- Fasudil Impurity 45 (CAS CATO-C4X-136545)
- Fasudil Impurity 41 (CAS 5769-35-7)
- Fasudil Impurity 27 (CAS 5451-44-5)
- Fasudil Impurity 22 (CAS CATO-C4X-136522)
- Fasudil Impurity 39 (CAS 4403-78-5)
- Fasudil Impurity 26 (CAS 4392-52-3)
- Fasudil Impurity 47 (CAS 105628-70-4)
Recommended Standards
- 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione (CAS 1312991-15-3)
- ((2R,3S,4R,5R)-5-(6-Amino-8-((8-aminooctyl)amino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 62209-07-8)
- 3-((3,5-Bis(trifluoromethyl)phenyl)amino)-4-(((1R,2R)-2-(piperidin-1-yl)cyclohexyl)amino)cyclobut-3-ene-1,2-dione (CAS 1211565-11-5)
- ((2S,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-((diethoxyphosphoryl)methyl)tetrahydrofuran-2-yl)methyl benzoate (CAS 90012-86-5)
- Cefoperazone Impurity 40 (CAS CATO-C4X-114948)
- Urapidil Impurity 6 (CAS 769-42-6)
- Aripiprazole EP Impurity B DiHCl (CAS 864512-47-0)
- 2-Amino-4-chloro-6-phenylpyrimidine (CAS 36314-97-3)
- n-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1073353-60-2)
- 3-Phenyl-5,6-dihydro-4H-pyrrolo[1,2-c][1,2,3]triazole (CAS 40930-12-9)
- N-(3-(trifluoromethyl)phenyl)thiophene-2-sulfonamide (CAS 332354-79-7)
- n'-Hydroxy-2-(morpholin-4-yl)ethanimidamide (CAS 5815-63-4)
- 5-Benzyl-5-azaspiro[3.5]nonan-8-amine (CAS 2361644-19-9)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com