Rifamycin Impurity 10 CAS 13553-79-2
| CAS No. | 13553-79-2 |
| Molecular Formula | C37H45NO12 |
| Molecular Weight | 695.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rifamycin Impurity 10 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rifamycin Impurity 10 (CAS 13553-79-2, C37H45NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C37H45NO12, Rifamycin Impurity 10 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 695.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rifamycin Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H45NO12 |
| Molecular Weight | 695.75 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 1 |
Related Rifamycin Standards
Recommended Standards
- Rifapentine impurity 20 (CAS CATO-C4X-195920)
- Qca570 (CAS 2207569-08-0)
- Z-Val-Asp(OMe)-Val-Ala-DL-Asp(OMe)-fluoromethylketone (CAS 1926163-61-2)
- Tetramycin (CAS 11076-50-9)
- Spiramycin EP Impurity H (CAS CATO-C1896290)
- Regadenoson Impurity 55 (CAS CATO-C4X-198555)
- Resmetirom impurity 18 (CAS 1581304-52-0)
- N-Benzyl([1,1-biphenyl]-4-yl)methanamine hydrochloride (CAS 1048640-47-6)
- 2,6-Dimethylnicotinoyl chloride (CAS 1215964-43-4)
- 1-(Ethoxymethyl)-3,4-dihydroisoquinoline (CAS 88422-90-6)
- 6-(Furan-2-yl)-3-phenylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 937597-65-4)
- (+)-3R,5S-Fluvastatin sodium salt (CAS 155229-75-7)
- 3-(3-Aminoazetidin-3-yl)phenyl acetate dihydrochloride (CAS 1384265-19-3)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com