Rifamycin impurity 20 CAS 32259-67-9
| CAS No. | 32259-67-9 |
| Molecular Formula | C36H43NO12 |
| Molecular Weight | 681.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rifamycin impurity 20.
As a process- or degradation-related impurity, Rifamycin impurity 20 (CAS 32259-67-9, C36H43NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rifamycin impurity 20 (C36H43NO12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 681.73 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rifamycin impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C36H43NO12 |
| Molecular Weight | 681.73 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Rifamycin Standards
Recommended Standards
- NSP-SA-NHS, 97% (CAS 199293-83-9)
- Suc-Ala-Lys-Pro-Phe-pNA (L-1630.0050) (CAS 128802-74-4)
- N-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide (CAS 945628-65-9)
- Tadalafil Impurity 98 (CAS CATO-C4X-108798)
- Tedizolid Impurity 52 (CAS 2095200-68-1)
- Moxifloxacin impurity 203 (CAS 1027303-55-4)
- Temozolomide Impurity 14 (CAS 100-34-5)
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- 3-((Naphthalen-1-yloxy)methyl)benzohydrazide (CAS 438474-98-7)
- 2-(Naphthalen-2-yloxy)propanoic acid (CAS 10470-82-3)
- 2-Chloro-5-[(3-methylpiperidin-1-yl)methyl]pyridine (CAS 861211-47-4)
- 149471-11-4 Neuropeptide DF2 L-Phenylalaninamide, L-alpha-aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl- Asp-arg-asn-phe-leu-arg-phe-NH2 Aspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamide L-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide DF(2) Neuropeptide Drnflrfamide (CAS 149471-11-4)
Why CATO?
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