1355729-47-3 2(1H)-Pyridinone, 6-chloro-5-(difluoromethyl)- CAS 1355729-47-3
| CAS No. | 1355729-47-3 |
| Molecular Formula | C6H4ClF2NO |
| Molecular Weight | 179.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1355729-47-3 2(1H)-Pyridinone, 6-chloro-5-(difluoromethyl)-.
CATO supplies 1355729-47-3 2(1H)-Pyridinone, 6-chloro-5-(difluoromethyl)- (CAS 1355729-47-3), a certified reference material (molecular formula C6H4ClF2NO, MW 179.55 g/mol) for analytical method development and quality control.
The molecular framework of 1355729-47-3 2(1H)-Pyridinone, 6-chloro-5-(difluoromethyl)- (C6H4ClF2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2NO |
| Molecular Weight | 179.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related H Standards
- 2(1H)-Pyridinone, 3-chloro-1,4,6-trimethyl- (CAS 2417310-80-4)
- 2(1H)-Pyridinone,3-Bromo-4-Hydroxy- (CAS 96245-97-5)
- 2(1H)-Pyridinone, 6-[(1E)-1-(methoxyimino)ethyl]- (CAS 2803981-29-3)
- 2(1H)-pyridinone, 4-amino-3,5,6-trifluoro- (CAS 105252-93-5)
- 2(1H)-Pyridinone, 3-(1-hydroxy-1-methylethyl)- (CAS 1536340-60-9)
- 2(1H)-Pyridinone, 5-nitro-6-(trifluoromethyl)- (CAS 117519-19-4)
- bis(2-pyridinone)oxime (CAS 1562-95-4)
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Recommended Standards
- 3-Chloro-5-(difluoromethoxy)pyridine (CAS 130115-88-7)
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- (4-Chloro-2,5-difluoropyridin-3-yl)methanol (CAS 1260788-41-7)
- 5-Chloro-1-(difluoromethyl)pyridin-2(1H)-one (CAS 1423016-46-9)
- Potassium Phosphate Hydrate (CAS 115281-28-2)
- 3-(6-(4-Chlorophenyl)imidazo[2,1-b]thiazol-3-yl)propanamide (CAS 1040647-27-5)
- Levomepromazine Maleate EP Impurity B (CAS 7606-29-3)
- 1-(4-Ethoxyphenyl)-4-(1-methyl-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 637322-30-6)
- 2-(1-Methyl-1H-imidazol-2-yl)phenol (CAS 52755-94-9)
- 2-(Sec-butylthio)-1-(2-fluorophenyl)ethan-1-one (CAS 1154194-65-6)
- 4-(2-Ethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 36017-22-8)
- 4-Chloro-2-iodothieno[2,3-b]pyridine (CAS 1574562-73-4)
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