5-(4-Chlorophenyl)nicotinamide CAS 1356110-72-9
| CAS No. | 1356110-72-9 |
| Molecular Formula | C12H9ClN2O |
| Molecular Weight | 232.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Chlorophenyl)nicotinamide.
5-(4-Chlorophenyl)nicotinamide (CAS 1356110-72-9) is a high-purity analytical reference standard with the molecular formula C12H9ClN2O and a molecular weight of 232.67 g/mol.
The molecular framework of 5-(4-Chlorophenyl)nicotinamide (C12H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-Chlorophenyl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O |
| Molecular Weight | 232.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-(2-(4-Chlorophenyl)-5-methyloxazol-4-yl)acetonitrile (CAS 1017181-96-2)
- 5-(3-Chlorophenyl)nicotinamide (CAS 1356110-60-5)
- 5-(2-Chlorophenyl)nicotinamide (CAS 1356110-63-8)
- 1-(4-Chlorophenyl)-2-(pyrimidin-2-yl)ethanone (CAS 1437433-85-6)
- N-(4-chlorophenyl)isonicotinamide (CAS 14547-69-4)
- n-(4-Chlorophenyl)picolinamide (CAS 14547-72-9)
- N-(4-chlorophenyl)nicotinamide (CAS 14621-03-5)
- 6-(4-Chlorophenyl)-3-methylimidazo[2,1-b]oxazole (CAS 191019-42-8)
Recommended Standards
- 2-Chloro-6-(2-hydroxyethyl)quinoline-3-carbonitrile (CAS 1367706-48-6)
- 2-(3-Amino-4-chloro-1h-pyrazol-1-yl)-n-(2-methoxyethyl)acetamide (CAS 1344066-59-6)
- 3-Chloro-N-(prop-2-yn-1-yl)-1H-indole-2-carboxamide (CAS 1437486-19-5)
- 3-(3-Chlorobenzoyl)pyridin-2-amine (CAS 1343767-60-1)
- N-methyl-1-(pyridin-4-ylmethyl)piperidin-4-amine (CAS 919280-64-1)
- 1',3',3'-Trimethyl-8-nitrospiro[chromene-2,2'-indoline] (CAS 5150-50-5)
- 2-Amino-9-(6-((6-chloro-2-methoxyacridin-9-yl)amino)hexyl)-1H-purin-6(9H)-one (CAS 103083-42-7)
- 7-Chloro-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid (CAS 27330-42-3)
- Tetraethylammonium Cyanide (CAS 13435-20-6)
- Triethoxyphosphine(trifluoroacetylacetonate)silver(I) (CAS 783334-85-0)
- Relugolix Impurity 174 (CAS CATO-C4X-2429174)
- 4-[(aminooxy)methyl]benzoic acid hydrochloride (CAS 20228-85-7)
- (Z)-1-(4-chlorophenyl)-3-(dimethylamino)-2-(ethylsulfonyl)prop-2-en-1-one 1823194-72-4 KS-000025T9 (CAS 1823194-72-4)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
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