N-(4-chlorophenyl)isonicotinamide CAS 14547-69-4
| CAS No. | 14547-69-4 |
| Molecular Formula | C12H9ClN2O |
| Molecular Weight | 232.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 232.67 g/mol gives N-(4-chlorophenyl)isonicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-chlorophenyl)isonicotinamide (CAS 14547-69-4) is a high-purity analytical reference standard with the molecular formula C12H9ClN2O and a molecular weight of 232.67 g/mol.
The molecular framework of N-(4-chlorophenyl)isonicotinamide (C12H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-chlorophenyl)isonicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O |
| Molecular Weight | 232.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 2-(2-(4-Chlorophenyl)-5-methyloxazol-4-yl)acetonitrile (CAS 1017181-96-2)
- 5-(3-Chlorophenyl)nicotinamide (CAS 1356110-60-5)
- 5-(2-Chlorophenyl)nicotinamide (CAS 1356110-63-8)
- 5-(4-Chlorophenyl)nicotinamide (CAS 1356110-72-9)
- 1-(4-Chlorophenyl)-2-(pyrimidin-2-yl)ethanone (CAS 1437433-85-6)
- n-(4-Chlorophenyl)picolinamide (CAS 14547-72-9)
- N-(4-chlorophenyl)nicotinamide (CAS 14621-03-5)
- 6-(4-Chlorophenyl)-3-methylimidazo[2,1-b]oxazole (CAS 191019-42-8)
Recommended Standards
- 3-Chloro-N-(prop-2-yn-1-yl)-1H-indole-2-carboxamide (CAS 1437486-19-5)
- 2-Chloro-6-(2-hydroxyethyl)quinoline-3-carbonitrile (CAS 1367706-48-6)
- 6-chloro-3-methoxypyrrolo[1,2-a]quinoxaline (CAS 160657-08-9)
- 4-Chloro-9-methoxypyrrolo[1,2-a]quinoxaline (CAS 1616253-02-1)
- 5-Chloro-1-methyl-3-((5-phenyl-1,3,4-oxadiazol-2-yl)imino)indolin-2-one (CAS 84640-88-0)
- 6-Bromo-8-methyl-2-propylquinolin-4-amine (CAS 1189105-94-9)
- Benzo[1,2-b;4,5-b']bisbenzofuran" (CAS 208-37-7)
- Ethyl 4-bromo-7-methoxyquinoline-6-carboxylate (CAS 2089325-50-6)
- (4,4'-Didodecyl-[2,2'-bithiophene]-5,5'-diyl)bis(trimethylstannane) (CAS 1007347-63-8)
- Methyl 2-acetyl-6-formylisonicotinate (CAS 1393569-00-0)
- 6-chloro-2-methyl-2,3-dihydropyridazin-3-one (CAS 10071-38-2)
- 3-(4-Chlorophenyl)-2-oxo-2H-chromen-7-yl propionate (CAS 869080-11-5)
- 3-(2,5-Dimethoxyphenyl)prop-2-yn-1-ol (CAS 850079-43-5)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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