5-Fluoro-2-(iodomethyl)-2,3-dihydrobenzofuran CAS 135634-29-6
| CAS No. | 135634-29-6 |
| Molecular Formula | C9H8FIO |
| Molecular Weight | 278.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-2-(iodomethyl)-2,3-dihydrobenzofuran.
5-Fluoro-2-(iodomethyl)-2,3-dihydrobenzofuran (CAS 135634-29-6) is a high-purity analytical reference standard with the molecular formula C9H8FIO and a molecular weight of 278.06 g/mol.
5-Fluoro-2-(iodomethyl)-2,3-dihydrobenzofuran (C9H8FIO) contains a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-2-(iodomethyl)-2,3-dihydrobenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8FIO |
| Molecular Weight | 278.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
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Recommended Standards
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- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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