2-Iodo-N-methoxy-5-nitrobenzamide CAS 1356754-44-3
| CAS No. | 1356754-44-3 |
| Molecular Formula | C8H7IN2O4 |
| Molecular Weight | 322.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Iodo-N-methoxy-5-nitrobenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Iodo-N-methoxy-5-nitrobenzamide (CAS 1356754-44-3) is a high-purity analytical reference standard with the molecular formula C8H7IN2O4 and a molecular weight of 322.06 g/mol.
The molecular framework of 2-Iodo-N-methoxy-5-nitrobenzamide (C8H7IN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Iodo-N-methoxy-5-nitrobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7IN2O4 |
| Molecular Weight | 322.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Iodo Standards
- Methyl 4-iodo-2,6-dimethoxybenzoate (CAS 1401110-37-9)
- 3-Iodo-5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridine (CAS 1422442-81-6)
- Methyl 2-iodo-4,6-dimethoxybenzoate (CAS 160191-48-0)
- 3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 1627924-17-7)
- Methyl 3-(4-iodo-1H-pyrrole-2-carboxamido)propanoate (CAS 1706452-70-1)
- 2-Iodo-4,5-dimethoxybenzoic acid methyl ester (CAS 173043-61-3)
- Methyl 2-(5-iodo-2-methoxyphenoxy)acetate (CAS 183803-04-5)
- 2-(2-Iodo-4,5-dimethoxyphenyl)acetic acid (CAS 35323-09-2)
Recommended Standards
- 2-(Carboxymethoxy)-5-iodobenzoic acid (CAS 60770-26-5)
- Methyl 2-amino-3-iodo-5-nitrobenzoate (CAS 1427501-54-9)
- (2-Bromo-4,6-bis(trifluoromethyl)phenyl)methanamine (CAS 1805512-83-7)
- Methyl 4-amino-3-iodo-5-nitrobenzoate (CAS 172221-28-2)
- Cyclobutyl 2-(3,4-dimethylphenyl)ethyl ketone (CAS 898779-97-0)
- 6'-Fluoro-1'H-spiro[piperidine-4,2'-quinolin]-4'(3'H)-one (CAS 2446846-23-5)
- 1,4-dichloro-2,5-dinitrobenzene (CAS 17488-24-4)
- 4-{[3-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl)propanamido]methyl}benzoic acid (CAS 451466-07-2)
- 3-Bromo-5-methyl-5H-pyrrolo[2,3-b]pyrazine (CAS 1270496-91-7)
- N-(4-chlorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide (CAS 882749-31-7)
- Rifapentine Impurity N1 (3-Formyl-Desacetyl Rifapentine) (CAS 16783-97-4)
- 4-Methoxy-6-(methylselanyl)pyrimidin-2-amine (CAS 100559-66-8)
- (6AS,6a'S)-3,3'-(propane-1,3-diylbis(oxy))bis(2-methoxy-7,12-dihydrobenzo[5,6][1,4]diazepino[1,2-b]isoquinolin-14(6aH)-one) (CAS 1971075-99-6)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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