2-Bromo-5-(piperidin-1-yl)-1,3,4-thiadiazole CAS 1357147-48-8
| CAS No. | 1357147-48-8 |
| Molecular Formula | C7H10BrN3S |
| Molecular Weight | 248.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrile group, sulfur-containing functionality, bromine substitution, an aromatic ring system, 2-Bromo-5-(piperidin-1-yl)-1,3,4-thiadiazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 248.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromo-5-(piperidin-1-yl)-1,3,4-thiadiazole (CAS 1357147-48-8), molecular formula C7H10BrN3S and molecular weight 248.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-5-(piperidin-1-yl)-1,3,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10BrN3S |
| Molecular Weight | 248.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-((5-Bromothiophen-2-yl)methoxy)azetidine (CAS 1339802-82-2)
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- 3-((4-Bromothiophen-2-yl)methyl)azetidin-3-ol (CAS 1483181-78-7)
- 3-((4-Bromothiophen-2-yl)methoxy)azetidine (CAS 1309315-52-3)
- 1-(6-Aminopyridin-3-yl)propan-1-one (CAS 1355218-29-9)
- 2,6-Bis(hydroxymethyl)pyrimidin-4(1H)-one (CAS 193071-37-3)
- 6-(Thiophen-2-yl)-1H-imidazo[1,2-b]pyrazole (CAS 130598-89-9)
- Ethyl 3-acetamido-4-cyclopropyl-4-oxobutanoate (CAS 1823601-07-5)
- 2-Ethoxythiazole (CAS 15679-19-3)
- 3-Chloro-2-(pyridin-2-ylthio)-5-(trifluoromethyl)pyridine (CAS 1024379-08-5)
- (3,4-Dimethoxy-benzyl)-pyridin-3-ylmethyl-amineoxalate (CAS 1050161-44-8)
- (S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)butan-1-amine (CAS 1213028-26-2)
- 2-Isopropyl-6-oxa-2,9-diazaspiro[4.5]decane (CAS 1707402-99-0)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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