Palonosetron Hydrochloride CAS 135729-62-3
| CAS No. | 135729-62-3 |
| Molecular Formula | C19H24N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Palonosetron Hydrochloride.
CATO supplies Palonosetron Hydrochloride (CAS 135729-62-3), a certified reference material (molecular formula C19H24N2OHCl, MW 332.87 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Palonosetron Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24N2O HCl |
| Molecular Weight | 332.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Palonosetron Standards
- Palonosetron USP Related Compound B (CAS 1021456-82-5)
- Palonosetron Impurity 7 (CAS 120570-05-0)
- Palonosetron Impurity 34 (CAS 1227162-74-4)
- Palonosetron USP Related Compound E HCl (CAS 135729-55-4)
- Palonosetron-3-ene (CAS 135729-56-5)
- Palonosetron (CAS 135729-61-2)
- Palonosetron Impurity N64 (CAS 135729-66-7)
- Palonosetron USP Related Compound C HCl (CAS 135729-76-9)
Recommended Standards
- 3-(3,4-Diethoxyphenethyl)-2-thioxoimidazolidin-4-one (CAS 832738-19-9)
- Ethyl 5-amino-3-bromo-1-methyl-1H-pyrazole-4-carboxylate (CAS 1934857-77-8)
- 1-(4-Methoxyphenyl)pyrazolidine-3,5-dione (CAS 591233-83-9)
- 6,8-Dichloro-3-methyl-4H-chromen-4-one (CAS 57645-95-1)
- N-nitroso DL-Praziquanamine (CAS 115822-46-3)
- Atropine Impurity 45 (CAS 2515-36-8)
- N1,N1,N1,N3,N3,N3-Hexamethylpropane-1,3-diaminium chloride (CAS 56971-22-3)
- 1-Chloro-8-nitroanthracene-9,10-dione (CAS 129-38-4)
- 7-fluoro-1,5-naphthyridine-4-carboxylic acid (CAS 1437790-02-7)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com