1-Methyl-4-(pyrrolidin-3-yl)-1H-pyrazole hydrochloride CAS 1359656-23-7
| CAS No. | 1359656-23-7 |
| Molecular Formula | C8H13N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Methyl-4-(pyrrolidin-3-yl)-1H-pyrazole hydrochloride (C8H13N3HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-Methyl-4-(pyrrolidin-3-yl)-1H-pyrazole hydrochloride (CAS 1359656-23-7), molecular formula C8H13N3HCl and molecular weight 187.67 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13N3 HCl |
| Molecular Weight | 187.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 1000018-40-5 3-pyrrolidin-1-yl-4-(methylsulphonyl)aniline 4-Methylsulfonyl-3-(pyrrolidin-1-yl)aniline (CAS 1000018-40-5)
- Ethyl 2-(pyrrolidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 1000339-79-6)
- 2-[4-(Pyrrolidin-3-yloxy)phenyl]ethylamine (CAS 1000507-30-1)
- 4-(Pyrrolidin-3-yl)-1H-pyrazole (CAS 1000772-62-2)
- 1-(2-(Pyrrolidin-1-yl)ethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1000802-52-7)
- 1-(Pyrrolidin-1-ylsulfonyl)-4,4'-bipiperidine (CAS 1000958-63-3)
- 2-PYrrolidin-3-yl-1h-pyrrolo[2,3-b]pyridine dihydrochloride (CAS 1001069-32-4)
- (1-(Pyrrolidin-1-ylmethyl)cyclopropyl)methanamine dihydrochloride (CAS 1001345-81-8)
Recommended Standards
- tert-Butyl 4-((4-bromo-2-fluorobenzyl)oxy)piperidine-1-carboxylate (CAS 1704095-50-0)
- 7-Bromoquinoline-3-carbonitrile (CAS 1375108-40-9)
- 2-Bromo-4-fluoro-N-(2-fluorobenzyl)aniline (CAS 1038976-20-3)
- N-cyclopropyl-2H-1,2,3-triazole-4-carboxamide (CAS 1344096-92-9)
- 4-bromo-7-fluoropyrazolo[1,5-a]pyridine (CAS 1427434-65-8)
- 3-Methylcycloheptanone (CAS 933-17-5)
- 5-Iodo-2-propoxyaniline (CAS 1310099-25-2)
- 1-Amino-n,n-dimethylcyclopentane-1-carboxamide (CAS 858603-76-6)
- 4,6-Difluoro-2-methylpyrimidine (CAS 18382-80-4)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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