4,6-Difluoro-2-methylpyrimidine CAS 18382-80-4
| CAS No. | 18382-80-4 |
| Molecular Formula | C5H4F2N2 |
| Molecular Weight | 130.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Difluoro-2-methylpyrimidine (C5H4F2N2) contains a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4,6-Difluoro-2-methylpyrimidine (CAS 18382-80-4) is a high-purity analytical reference standard with the molecular formula C5H4F2N2 and a molecular weight of 130.10 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,6-Difluoro-2-methylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4F2N2 |
| Molecular Weight | 130.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 3,6-Difluoro-4-methylpyridazine (CAS 1026843-07-1)
- 4,6-difluoro-5-methylpyrimidine (CAS 18260-64-5)
- 2,4-difluoro-5-methylpyrimidine (CAS 96548-89-9)
- 2,4-Difluoro-6-methylpyrimidine (CAS 696-80-0)
- 4,6-Difluoro-2-pyridinamine (CAS 938443-45-9)
- 3,5-Difluoro-1H-pyridin-2-one (CAS 914482-23-8)
- 2,4-Difluoro-5-methylpyridine (CAS 1227502-70-6)
- 2,5-Difluoro-4-methylpyridine (CAS 1227508-13-5)
Recommended Standards
- 2,5-Difluoropyridin-4-amine (CAS 189281-61-6)
- 5,6-Difluoropyridin-2-amine (CAS 1807159-28-9)
- (+/-)-Paraconic acid (CAS 498-89-5)
- 3,4-Difluoropyridin-2-amine (CAS 1804379-06-3)
- cis-7-Fluorohexahydroindolizin-3(2H)-one (CAS 148855-27-0)
- Methyl 4-amino-3-isopropoxybenzoate, 97% (CAS 681465-85-0)
- (S)-2-Amino-1-((S)-3-(benzyl(ethyl)amino)piperidin-1-yl)-3-methylbutan-1-one (CAS 1401667-82-0)
- 2,3-dimethyl-4'-piperidinomethyl benzophenone (CAS 898775-05-8)
- (2-(Hydroxymethyl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2121513-82-2)
- 4,5-Diamino-1H-pyridazin-6-one (CAS 28682-73-7)
- 2-(Methylamino)-1-(4-(3-methylbenzyl)piperazin-1-yl)ethan-1-one hydrochloride (CAS 1177350-98-9)
- (2,5-Dibromophenyl)hydrazine hydrochloride (CAS 214915-87-4)
- Lovastatin Impurity N1 (CAS 106909-04-0)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com