2-(2-Chlorophenyl)-6,7-difluoroquinazolin-4(3H)-one CAS 1361457-75-1
| CAS No. | 1361457-75-1 |
| Molecular Formula | C14H7ClF2N2O |
| Molecular Weight | 292.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(2-Chlorophenyl)-6,7-difluoroquinazolin-4(3H)-one (CAS 1361457-75-1), molecular formula C14H7ClF2N2O and molecular weight 292.67 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(2-Chlorophenyl)-6,7-difluoroquinazolin-4(3H)-one (C14H7ClF2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 292.67 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF2N2O |
| Molecular Weight | 292.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- N,N,4-Trimethyl-3-nitrobenzenesulfonamide (CAS 96-57-1)
- β-Cyclopropyl-4-fluoro-3-methylbenzenepropanoic acid (CAS 1017330-08-3)
- 4-(2-(4-Nitrophenoxy)ethoxy)aniline hydrochloride (CAS 19157-80-3)
- Ethyl 2-(5-fluoro-2-nitrophenyl)acetate (CAS 121303-77-3)
- 4-[2-nitro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine (CAS 1527471-35-7)
- 2-(1-methyl-1H-benzimidazol-2-yl)-1-phenylethanone (CAS 58112-93-9)
- 1-{2-[(4-chloro-1-naphthyl)oxy]ethyl}piperazine hydrochloride (CAS 1609396-35-1)
- 4-[5-(aminomethyl)furan-2-yl]benzene-1-sulfonamide hydrochloride (CAS 1172734-38-1)
- 1-(2-(Ethylsulfonyl)ethyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1157828-83-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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