2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonamide CAS 1361468-18-9
| CAS No. | 1361468-18-9 |
| Molecular Formula | C8H8F5N3O2S |
| Molecular Weight | 305.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonamide (CAS 1361468-18-9) is a high-purity analytical reference standard with the molecular formula C8H8F5N3O2S and a molecular weight of 305.23 g/mol.
2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonamide (C8H8F5N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8F5N3O2S |
| Molecular Weight | 305.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-3-(difluoromethyl)-4-(trifluoromethyl)pyridine-5-sulfonamide (CAS 1361702-20-6)
- 2-(Aminomethyl)-5-(difluoromethyl)-4-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1361702-29-5)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-(trifluoromethyl)pyridine-6-sulfonamide (CAS 1361734-74-8)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-6-sulfonamide (CAS 1361734-82-8)
- 2-(Aminomethyl)-5-(difluoromethyl)-6-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1361751-39-4)
- 4-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethyl)pyridine-2-sulfonamide (CAS 1361751-48-5)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-6-sulfonamide (CAS 1361785-49-0)
- 4-(Aminomethyl)-6-(difluoromethyl)-5-(trifluoromethyl)pyridine-3-sulfonamide (CAS 1361815-45-3)
Recommended Standards
- Ethyl 4,6-bis(difluoromethyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylate (CAS 1354705-89-7)
- 1-(4-Bromothiophen-2-yl)-N-((4-methylmorpholin-2-yl)methyl)methanamine (CAS 1333640-96-2)
- 1-(5-Bromothiophen-2-yl)-N-((4-methylmorpholin-2-yl)methyl)methanamine (CAS 1280931-35-2)
- 2-(4-((5-Bromothiophen-3-yl)methyl)piperazin-1-yl)ethan-1-ol (CAS 1248743-98-7)
- 3-[2-(4-Bromo-2-fluorophenoxy)ethyl]piperidinehydrochloride (CAS 1219964-30-3)
- 4-((Vinyloxy)methyl)cyclohex-1-ene (CAS 613684-57-4)
- Methyl s-isopropylhomocysteinate (CAS 1500649-95-5)
- N-[2-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide (CAS 2246619-60-1)
- 2-Butyl-4-chloro-5-((2,4-dichlorobenzyl)oxy)pyridazin-3(2H)-one (CAS 88094-29-5)
- 5-Boc-4,5,6,7-Tetrahydropyrazolo[4,3-c]pyridine (CAS 230301-11-8)
- 3-(2-tert-butyl-1H-1,3-benzodiazol-1-yl)propanoic acid hydrochloride (CAS 1432679-62-3)
- 9-(4-Bromonaphthalen-1-yl)-10-phenylanthracene (CAS 1062556-32-4)
- Ethyl 5-((tert-butoxycarbonylamino)methyl)-1,2,4-oxadiazole-3-carboxylate (CAS 164029-34-9)
- Peptide 436 (CAS CATO-CPTD788436)
Why CATO?
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