2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine CAS 1361468-48-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1361468-48-5
Molecular FormulaC9H9F5N2O
Molecular Weight256.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine CAS 1361468-48-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine.

2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine (CAS 1361468-48-5), molecular formula C9H9F5N2O and molecular weight 256.17 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine (C9H9F5N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 256.17 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H9F5N2O
Molecular Weight256.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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