5-Amino-2-(trifluoromethoxy)pyridin-4-ol CAS 1361812-52-3
| CAS No. | 1361812-52-3 |
| Molecular Formula | C6H5F3N2O2 |
| Molecular Weight | 194.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-(trifluoromethoxy)pyridin-4-ol.
CATO supplies 5-Amino-2-(trifluoromethoxy)pyridin-4-ol (CAS 1361812-52-3), a certified reference material (molecular formula C6H5F3N2O2, MW 194.11 g/mol) for analytical method development and quality control.
The molecular framework of 5-Amino-2-(trifluoromethoxy)pyridin-4-ol (C6H5F3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Amino-2-(trifluoromethoxy)pyridin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5F3N2O2 |
| Molecular Weight | 194.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-2,4-dihydroxy-6-(trifluoromethyl)pyridine (CAS 1214365-75-9)
- 2-AMino-6-hydroxy-1,3-benzoxazole-5-carboxylic acid (CAS 2055119-38-3)
- 2-Amino-3,4-dichlorobenzenethiol (CAS 126764-57-6)
- 2-Amino-4,6-dichlorobenzenethiol (CAS 131105-96-9)
- 2-Amino-3,5-dichlorobenzene-1-thiol (CAS 152874-01-6)
- 2-Amino-4,5-dichlorobenzenethiol (CAS 6647-24-1)
- 6-Amino-2,3-dichlorobenzenethiol (CAS 6647-25-2)
- 3-Amino-5-(1,1,1-trifluoro-2-methyl-2-propyl)isoxazole (CAS 1188911-74-1)
Recommended Standards
- 5-(2,2,2-Trifluoroethoxy)pyridazin-3(2H)-one (CAS 1346697-88-8)
- 2-(5-(Trifluoromethyl)-1H-imidazol-4-yl)acetic acid (CAS 1367850-96-1)
- 1-(2,2,2-Trifluoroethyl)pyrimidine-2,4(1H,3H)-dione (CAS 1340213-90-2)
- 2-(5-(Trifluoromethyl)-1H-pyrazol-3-yl)acetic acid (CAS 1374032-37-7)
- 5-(Pyridin-3-yl)isoxazole (CAS 102189-83-3)
- 1,1'-diethyl-2,2'-dicarbocyanine iodide (CAS 14187-31-6)
- 6-(Trifluoromethyl)nicotinimidamide (CAS 438249-89-9)
- Methyl 2-(4-Isothiocyanatophenyl)acetate (CAS 77055-43-7)
- 6-Chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt, 97% (CAS 138182-20-4)
- 6-Benzooxazol-2-ylbenzothiazol-2-ylamine (CAS 301321-03-9)
- 4-(2-Hydroxyethyl)-1-phenylpyrazolidin-3-one (CAS 113410-22-3)
- 15-Keto Bimatoprost (CAS 1163135-96-3)
- 1,3-Phenylenebis((4-fluorophenyl)methanone) (CAS 108464-88-6)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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