3-Bromo-2-chloro-5-(trifluoromethoxy)pyridine CAS 1361852-33-6
| CAS No. | 1361852-33-6 |
| Molecular Formula | C6H2BrClF3NO |
| Molecular Weight | 276.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-2-chloro-5-(trifluoromethoxy)pyridine (CAS 1361852-33-6), molecular formula C6H2BrClF3NO and molecular weight 276.44 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Bromo-2-chloro-5-(trifluoromethoxy)pyridine (C6H2BrClF3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 276.44 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClF3NO |
| Molecular Weight | 276.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidin-2-amine (CAS 1240598-08-6)
- 2-Bromo-4-chloro-3-(trifluoromethoxy)pyridine (CAS 1361499-17-3)
- 3-Bromo-2-chloro-6-(trifluoromethoxy)pyridine (CAS 1361681-57-3)
- 4-Bromo-2-chloro-5-(trifluoromethoxy)pyridine (CAS 1361681-64-2)
- 3-Bromo-6-chloro-2-(trifluoromethoxy)pyridine (CAS 1361852-53-0)
- 5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine (CAS 1361852-60-9)
- 5-Bromo-2-chloro-6-(trifluoromethyl)pyrimidin-4-amine (CAS 1823954-38-6)
- 3-bromo-6-chloro-5-nitro-1H-indazole (CAS 1000342-41-5)
Recommended Standards
- 3,7-Bis(methylthio)dibenzo[b,d]thiophene (CAS 185540-18-5)
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- 3-(Decyloxy)tetrahydrothiophene 1,1-dioxide (CAS 18760-44-6)
- 2,6-Diphenyl-4<I>H</I>-thiopyran-4-one (CAS 1029-96-5)
- Ethyl 3-(3-bromo-4-fluorophenyl)-3-oxopropanoate (CAS 936125-75-6)
- Dimethylcarbamoyl-methanesulfonyl chloride (CAS 100481-28-5)
- 4-methanesulfonylthiophene-2-carboxylic acid (CAS 100704-38-9)
- (4-Bromo-1-methyl-2-nitro-1H-imidazol-5-yl)methanol (CAS 1092554-28-3)
- Metofluthrin (CAS 240494-70-6)
- Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium acetate (CAS 13106-14-4)
- Methyl (3,4-dimethoxybenzoyl)glycinate (CAS 72719-18-7)
- N-(2-Morpholinoethyl)-3-phenylimidazo[1,2-a]pyrazin-8-amine (CAS 787590-65-2)
- Fmoc-Asp(OtBu)-Ser(Psi(Me,Me)pro)-OH (CAS 955048-92-7)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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